Laing O'Rourke has been appointed by Barking and Dagenham Council to deliver its £270m Building Schools for the Future Programme (BSF).
The contractor will rebuild or refurbish every secondary school in the borough, plus the Trinity Special School.
Laing O'Rourke pipped Bouygues to the contract after a 10-month procurement and selection process.
The initial phase of construction, which will commence in February 2011, will involve the renewal of Dagenham Park Church of England School and The Sydney Russell School.
Upgrades of other schools will commence between January 2012 and June 2013 with all construction work completed by April 2015.
All construction and facilities management will be carried out by Laing O'Rourke. Information Communications Technology (ICT) services across all the schools will be delivered in conjunction with RM, a leading provider of ICT educational solutions.
Councillor Rocky Gill, deputy leader and cabinet member for education and children, said: "We have selected our Preferred Partner through a very stringent selection and scoring process. Building Schools for the Future represents the best opportunity to invest in our schools for generations."
Barking and Dagenham Council will now form a Local Education Partnership (LEP) with Laing O'Rourke. This will be the body responsible for delivering the BSF programme in Barking and Dagenham.
Mark Richardson, business unit leader, Laing O'Rourke Construction South, said: "We look forward to cementing a close partnership with the Borough through the Local Education Partnership, supporting their aspirations for more prosperous communities, and delivering outstanding designs and value for all schools in the programme."