The full planning application will be lodged with Aberdeen City Council later this month.
The scheme will transform the former St. Nicholas House site and include a greater prominence for the 469-year-old Provost Skene's House.
Demolition work at the site is currently under way.
Muse and Aberdeen City Council have taken account of comments made by the 2,500 people during two rounds of consultation exhibitions in the city late last year by reviewing the site plan in terms of the mix of commercial and civic space.
Marischal Square, which is fully funded by Aviva Investors, will deliver a mixed-use quarter for the city and include offices with associated car parking, hotel, retail, cafes, restaurants and civic space. The site was once dominated by the former council headquarters building St. Nicholas House.
The site is due to be handed over to Muse later this year ahead of the scheme being completed in 2017.
Councillor Marie Boulton, deputy leader of Aberdeen City Council said: "The response by the public to Muse's consultation has been fantastic. The proposals have generated a huge amount of interest and I am sure that interest will continue as the final proposals are laid out.”
The council's director of enterprise, planning and infrastructure Gordon McIntosh said: "We are delighted that Muse has been able to balance the essential commercial requirements of the development, the views of the public through the consultation, and the principles of good design to create a positive development on a key city site."