The contract with Wates will see the construction and refurbishment of new and existing buildings as part of scheduled works for the development on Cledford Lane. The 10-month project begins on 23rd May 2016.
The value of the contract was not disclosed.
The council is also investing £1m into constructing an air treatment system to minimise the impact of odour from the site.
Councillor Don Stockton said: “This project will put our residents first by maximising recycling efforts and reducing landfill to an absolute minimum. Residents local to the site will benefit from the fact that Cheshire East Council has chosen a construction partner that understands the vital role that local community involvement can have.”