More than 100 companies have expressed interested in taking over the Olympic Stadium after 2012, according to the organisation charged with managing the Games legacy.
The formal bidding process to take over the stadium has begun, and the Olympic Park Legacy Company (OPLC), said any organisations wishing to take over the Stratford arena have six weeks left to make their formal bid.
West Ham United Football Club, which estimates it will cost £180m to convert the venue into a 60,000-seater football stadium, and AEG, which runs the O2 Arena, are both thought to be in the running.
The OPLC has said the successful bid must retain the stadium as a "distinctive physical symbol" and support the regeneration of the area.
The bidding phase ends on 30 September, when the OPLC will select a shortlist.
Margaret Ford, chairwoman of the OPLC, said: "The stadium is at the heart of the Olympic Park and securing the solution is crucial to our long-term aspirations for the area.
"We aim to have selected a tenant by the end of the financial year."
Currently, plans are for the stadium to be downgraded from its 80,000 capacity during the Olympics to a 25,000-seat arena after the Games, for use as an athletics venue for the capital.