Mace will develop pre-construction plans, detailed construction programmes and work with the club to procure specialist subcontract tenders for the new stadium works.
The £400m development project will also include 579 new apartments and a 180-room hotel. The new stadium will hold 61,000 spectators when completed in 2018, according to plans.
Spurs chairman Daniel Levy said: “This is another step towards the delivery of one of the best stadiums in the world. We are delighted to have Mace on board. They bring a wealth of experience and I know they share our commitment to ensuring that the development will be first class in every aspect. We now await Haringey Council's planning committee decision on 8th December 2015.”
Mace chief executive Mark Reynolds said: “We are privileged and thrilled to join the team to take the new stadium to its next stage of development. We look forward to working with the club and its consultants to make sure the project is a success. It is of critical importance as it is the flagship development that will act as a catalyst for the regeneration of this area."